Search results for " Nifedipine"

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Surgical sphincter saving approach and topical nifedipine for chronic anal fissure with hypertonic internal anal sphincter

2020

PURPOSE The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days…

medicine.medical_specialtyLidocaineNifedipinemedicine.medical_treatmentAdministration TopicalAnal CanalSurgical FlapsInternal anal sphincterFissurectomyOintmentsMuscle HypertoniaNifedipineMuscle HypertoniamedicineHumansProspective StudiesAnesthetics LocalAnestheticsAnal fissureAnal fissure Anoplasty Fissurectomy Lidocaine Nifedipine Proctology Administration Topical Anal Canal Anesthetics Local Calcium Channel Blockers Chronic Disease Combined Modality Therapy Humans Lidocaine Muscle Hypertonia Ointments Prospective Studies Surgical Flaps Treatment Outcome Fissure in Ano Nifedipinebusiness.industryLidocaineAnal canalAnoplastymedicine.diseaseCalcium Channel BlockersCombined Modality TherapySurgerymedicine.anatomical_structureTreatment OutcomeTopicalLocalAdministrationChronic DiseaseHypertoniaSurgeryFissure in Anomedicine.symptomAnal fissureProctologyLateral internal sphincterotomybusinessmedicine.drug
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